(3R)-1-Benzyloxycarbonyl-3-methylpiperazine
(R)-4-Cbz-2-methylpiperazine
CAS: 623586-00-5
Molecular Formula: C13H18N2O2
(3R)-1-Benzyloxycarbonyl-3-methylpiperazine - Names and Identifiers
| Name | (R)-4-Cbz-2-methylpiperazine |
| Synonyms | (R)-4-CBZ-2-METHYLPIPERAZINE (R)-1-CBz-3-methylpiperazine (R)-4-Cbz-2-methylpiperazine 1-CBZ-(R)-3-METHYLPIPERAZINE 4-CBZ-(R)-2-METHYL PIPERAZINE (R)-4-Benzoxycarbonyl-2-methylpiperazine 4-BENZOXYCARBONYL-2-(R)-METHYLPIPERAZINE 4-N-BENZOXYCARBONYL-2-(R)-METHYLPIPERAZINE (3R)-1-Benzyloxycarbonyl-3-methylpiperazine (3R)-1-Benzyloxycarbonyl-3-methylpiperazine benzyl (3R)-3-methylpiperazine-1-carboxylate |
| CAS | 623586-00-5 |
| InChI | InChI=1/C13H18N2O2/c1-11-9-15(8-7-14-11)13(16)17-10-12-5-3-2-4-6-12/h2-6,11,14H,7-10H2,1H3/t11-/m1/s1 |
(3R)-1-Benzyloxycarbonyl-3-methylpiperazine - Physico-chemical Properties
| Molecular Formula | C13H18N2O2 |
| Molar Mass | 234.29 |
| Density | 1.105±0.06 g/cm3(Predicted) |
| Boling Point | 358.0±30.0 °C(Predicted) |
| Flash Point | 170.3°C |
| Vapor Presure | 2.62E-05mmHg at 25°C |
| pKa | 8.50±0.40(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.53 |
(3R)-1-Benzyloxycarbonyl-3-methylpiperazine - Introduction
(R)-4-Cbz-2-methylpiperazine is an organic compound with the chemical name (R)-4-[(benzyloxy)carbonyl]-2-methylpiperazine, abbreviated as (R)-CBZ-MPZ. It is a white solid, soluble in solvents.
(R)-4-Cbz-2-methylpiperazine has important applications in the field of medicine. It is a chiral molecule that can be used in the synthesis of pharmaceutical intermediates and biologically active molecules. Because of its piperazine ring and methyl group in its molecular structure, it is often used as a precursor compound for gamma ubiquitinase (gamma-secretase) inhibitors in medicinal chemistry.
The common method for preparing (R)-4-Cbz-2-methylpiperazine is to react (R)-2-methylpiperazine with phenylacetyl chloride, and then react with sodium hydroxide to obtain the product.
Regarding safety information, since (R)-4-Cbz-2-methylpiperazine is an organic compound, care should be taken to prevent contact with skin, eyes and inhalation during handling and storage. Appropriate protective gloves and glasses should be worn during use to ensure that the operation is carried out in a well-ventilated environment. In addition, it is necessary to follow the safety procedures of the relevant laboratories and the relevant regulations on the use of chemicals.
(R)-4-Cbz-2-methylpiperazine has important applications in the field of medicine. It is a chiral molecule that can be used in the synthesis of pharmaceutical intermediates and biologically active molecules. Because of its piperazine ring and methyl group in its molecular structure, it is often used as a precursor compound for gamma ubiquitinase (gamma-secretase) inhibitors in medicinal chemistry.
The common method for preparing (R)-4-Cbz-2-methylpiperazine is to react (R)-2-methylpiperazine with phenylacetyl chloride, and then react with sodium hydroxide to obtain the product.
Regarding safety information, since (R)-4-Cbz-2-methylpiperazine is an organic compound, care should be taken to prevent contact with skin, eyes and inhalation during handling and storage. Appropriate protective gloves and glasses should be worn during use to ensure that the operation is carried out in a well-ventilated environment. In addition, it is necessary to follow the safety procedures of the relevant laboratories and the relevant regulations on the use of chemicals.
Last Update：2024-04-09 20:52:54
Supplier List
Product Name: 1-CBZ-(R)-3-METHYLPIPERAZINE Visit Supplier Webpage Request for quotation
CAS: 623586-00-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 623586-00-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 1-CBZ-(R)-3-METHYLPIPERAZINE Visit Supplier Webpage Request for quotation
CAS: 623586-00-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 623586-00-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History